Syneos Health is a leading fully-integrated life sciences services organization built to accelerate customer success. We partner with innovators across the drug development and commercialization continuum, helping them navigate complexity, anticipate change and accelerate progress.
We are seeking Clinical Trial Managers (CTMs) who are passionate about operational excellence, collaborative leadership, and delivering high-quality global clinical trials.
Job Responsibilities- Lead end-to-end clinical trial execution, ensuring delivery against timelines, quality standards, and budget
- Provide operational oversight of site management and monitoring activities, including on-site and centralized monitoring
- Identify, assess, and proactively mitigate clinical and operational risks using a risk-based management approach (RACT)
- Serve as the primary escalation point for CRAs, investigative sites, and cross-functional stakeholders
- Partner closely with Study Start-Up, Data Management, Biostatistics, Safety, and Patient Recruitment teams to drive milestone achievement
- Leverage integrated systems and data (CTMS, EDC, ePRO, TMF, dashboards) to monitor performance, trends, and risk indicators
- Ensure ongoing inspection readiness and compliance with ICH-GCP, SOPs, and global regulatory requirements
- Lead study-specific training and foster alignment across the clinical trial team
- Review metrics and operational data to anticipate challenges and implement timely solutions
- Mentor and support CRAs, contributing to a culture of accountability, continuous improvement, and collaboration
- Hands‑on Clinical Research Associate (CRA) experience, including on-site monitoring (not remote‑only)
- 2+ years of experience as a Clinical Trial Manager, preferably within a CRO environment
- Strong understanding of global clinical trial operations and site management
- Demonstrated success leading cross‑functional, global clinical teams
- Solid experience with risk‑based monitoring and centralized oversight models
- Deep knowledge of ICH‑GCP and international regulatory requirements
- Strong analytical, critical‑thinking, and problem‑solving capabilities
- Confident communicator with the ability to navigate complex stakeholder and sponsor environments
- Comfortable working in a global, matrixed organization
- Proficiency with clinical trial systems (CTMS, EDC, ePRO, TMF)
- Experience in oncology and/or ophthalmology is a strong asset
- Be part of a global, innovative organization with a strong and diverse pipeline of clinical programs
- Lead high‑impact, complex trials across multiple therapeutic areas
- Work in a collaborative, inclusive environment where your expertise and perspective matter
- Gain exposure to a wide range of sponsors—from emerging biotech to top global pharmaceutical companies
- Access clear pathways for career growth, leadership development, and continuous learning
$132,000 - $178,000 USD
Benefits DetailsWe provide benefits such as a company car or car allowance, health benefits (medical, dental & vision), company match 401(k), eligibility for an Employee Stock Purchase Plan, commissions/bonus based on performance, and flexible paid time off (PTO) and sick time. Certain states and municipalities have regulated paid sick time requirements, so eligibility may vary.
Additional InformationTasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. No contract or employment relationship is created herein. All procedures comply with applicable legislation, including the EU Equality Directive and the Americans with Disabilities Act, including provision of reasonable accommodations.
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